Genetic Associations with Hypertension: Meta-Analyses of Six Candidate Genetic Variants
نویسندگان
چکیده
منابع مشابه
Genetic Associations with Diabetes: Meta-Analyses of 10 Candidate Polymorphisms
AIMS The goal of our study is to investigate the combined contribution of 10 genetic variants to diabetes susceptibility. METHODS Bibliographic databases were searched from 1970 to Dec 2012 for studies that reported on genetic association study of diabetes. After a comprehensive filtering procedure, 10 candidate gene variants with informative genotype information were collected for the curren...
متن کاملMeta-analyses between 18 candidate genetic markers and overweight/obesity
AIMS The goal of our study is to investigate the associations between 18 candidate genetic markers and overweight/obesity. METHODS A total of 72 eligible articles were retrieved from literature databases including PubMed, Embase, SpingerLink, Web of Science, Chinese National Knowledge Infrastructure (CNKI), and Wanfang. Meta-analyses of 18 genetic markers among 56,738 controls and 48,148 over...
متن کاملAssociation between Genetic Variants of Nitric Oxide/cGMP Pathway and Susceptibility to Hypertension in Kermanshah Province
Background and purpose: Hypertension is a global health challenge due to its high prevalence and increased risk of cardiovascular disease. It is a multifactorial disease in which both genetic and environmental factors are involved. So far, a number of genes and pathways have been proposed to be associated with HTN, including the nitric oxide/cGMP pathway. To further clarify the role of NO /cGM...
متن کاملAssociation of six genetic variants with myocardial infarction.
Although various genes that confer susceptibility to myocardial infarction (MI) have been identified for Caucasian populations in genome-wide association studies (GWAS), genetic variants related to this condition in Japanese individuals have not been identified definitively. The aim of the present study was to examine an association of MI in Japanese individuals with 29 polymorphisms identified...
متن کاملGenetic associations of nonsynonymous exonic variants with psychophysiological endophenotypes.
We mapped ∼85,000 rare nonsynonymous exonic single nucleotide polymorphisms (SNPs) to 17 psychophysiological endophenotypes in 4,905 individuals, including antisaccade eye movements, resting EEG, P300 amplitude, electrodermal activity, affect-modulated startle eye blink. Nonsynonymous SNPs are predicted to directly change or disrupt proteins encoded by genes and are expected to have significant...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Genetic Testing and Molecular Biomarkers
سال: 2013
ISSN: 1945-0265,1945-0257
DOI: 10.1089/gtmb.2013.0080